The assumption that every pair of participants can talk without being overheard.
Why it matters: In practice ordinary encryption provides it, which brings math assumptions back in.
On the map: between every pair of parties, unconditional only with one-time-pad or QKD keys (in practice: TLS)
Unconditional MPC protocols assume every pair of parties can talk secretly and authentically[1].
That is only truly unconditional if the channels are protected with one-time pads or QKD keys. In practice they run over TLS, which brings back computational assumptions, including quantum vulnerability unless the key exchange is hybrid.
If any of these breaks, this breaks too.
If this breaks, these break with it.